\u65e0\u8bb0\u6027\u3001\u65f6\u7a7a\u6df7\u4e71\u3001\u8bcd\u4e0d\u8fbe\u610f\u3001\u60c5\u7eea\u6613\u8d77\u4f0f\u2026\u963f\u5179\u6d77\u9ed8\u75c7\uff08Alzheimer's disease\uff09\u5bfc\u81f4\u7684\u8111\u90e8\u529f\u80fd\u53d7\u635f\uff0c\u4f1a\u5f71\u54cd\u60a3\u8005\u7684\u751f\u6d3b\u53ca\u6027\u60c5\u3002\u8fd9\u79cd\u75be\u75c5\u4ee5\u5f80\u4e00\u76f4\u88ab\u8ba4\u5b9a\u4e3a\u201c\u65e0\u836f\u53ef\u533b\u201d\uff0c \u4f46\u968f\u7740\u533b\u836f\u9886\u57df\u7684\u53d1\u5c55\uff0c\u5df2\u4e3a\u60a3\u8005\u5e26\u6765\u8f6c\u673a\u3002\u517b\u548c\u533b\u9662\u8111\u795e\u7ecf\u79d1\u4e13\u79d1\u533b\u751f\u5434\u70b3\u8363\u533b\u751f\u8868\u793a\uff0c\u9488\u5bf9\u65e9\u53d1\u73b0\u3001\u65e9\u786e\u8bca\u7684\u963f\u5179\u6d77\u9ed8\u75c7\u60a3\u8005\uff0c\u8fd1\u5e74\u6765\u53ef\u4f7f\u7528\u751f\u7269\u5236\u5242\uff0c\u6e05\u9664\u6c89\u79ef\u5728\u8111\u5185\u7684\u5176\u4e2d\u4e00\u79cd\u81f4\u75c5\u300c\u5143\u51f6\u300d\u2014\u2014\u7c7b\u6dc0\u7c89\u86cb\u767d\uff08Amyloid proteins\uff09\uff0c\u6709\u52a9\u4e8e\u60a3\u8005\u5ef6\u957f\u6b63\u5e38\u751f\u6d3b\u7684\u65f6\u95f4\u3001\u51cf\u6162\u75c5\u60c5\u6076\u5316\uff0c\u540c\u65f6\u4e5f\u80fd\u51cf\u8f7b\u5bb6\u4eba\u548c\u62a4\u7167\u8005\u7684\u538b\u529b\uff01<\/p>\n\n\n\n
<\/p>\n\n\n\n
\u963f\u5179\u6d77\u9ed8\u75c7\u662f\u8ba4\u77e5\u969c\u788d\u75c7\uff08Dementia\uff09\u7684\u5176\u4e2d\u4e00\u79cd\uff0c\u5434\u533b\u751f\u8868\u793a\uff0c\u8fc7\u534a\u6570\u4e2a\u6848\u5c5e\u6b64\u7c7b\uff0c\u786e\u5207\u75c5\u56e0\u672a\u660e\u3002\u60a3\u8005\u6700\u5e38\u89c1\u7684\u8868\u73b0\u662f\u8bb0\u6027\u53d8\u5dee\u3001\u65f6\u95f4\u7a7a\u95f4\u6df7\u4e71\u4e0d\u6e05\u3001\u5931\u53bb\u65b9\u5411\u611f\u81f4\u8ff7\u8def\uff0c\u90e8\u5206\u66f4\u4f1a\u50cf\u597d\u83b1\u575e\u5f71\u661f\u5e03\u9c81\u65af\u00b7\u5a01\u5229\u65af\uff08Bruce Willis\uff09\u51fa\u73b0\u5931\u8bed\u6216\u6c9f\u901a\u80fd\u529b\u4e0b\u964d\u7b49\u60c5\u51b5\u3002<\/p>\n\n\n\n
\u300c\u90e8\u5206\u60a3\u8005\u6216\u4f1a\u51fa\u73b0\u793e\u4ea4\u529f\u80fd\u969c\u788d\uff0c\u7531\u672c\u6765\u5916\u5411\u3001\u6ce8\u91cd\u4eea\u8868\uff0c\u6e10\u6e10\u53d8\u5f97\u6c89\u9ed8\u3001\u4e0d\u4fee\u8fb9\u5e45\uff0c\u4ea6\u6709\u90e8\u5206\u4f1a\u51fa\u73b0\u6267\u884c\u53ca\u51b3\u7b56\u80fd\u529b\u7b49\u95ee\u9898\u3002\u90e8\u5206\u8f83\u665a\u671f\u7684\u963f\u5179\u6d77\u9ed8\u75c7\u60a3\u8005\uff0c\u751a\u81f3\u4f1a\u51fa\u73b0\u60c5\u7eea\u6ce2\u52a8\u53ca\u601d\u89c9\u5931\u8c03\u7b49\u75c7\u72b6\uff0c\u4f8b\u5982\u89c9\u5f97\u6709\u4eba\u5077\u94b1\u3001\u88ab\u5bb3\u7b49\u3002\u300d\u52a0\u4e0a\u963f\u5179\u6d77\u9ed8\u75c7\u4e00\u76f4\u88ab\u8ba4\u5b9a\u662f\u300c\u65e0\u96be\u95fb\u300d\u7684\u75be\u75c5\u3002<\/p>\n\n\n\n
<\/p>\n\n\n\n
\u517b\u548c\u533b\u9662\u8111\u795e\u7ecf\u79d1\u4e13\u79d1\u533b\u751f\u5434\u70b3\u8363\u533b\u751f\u8868\u793a\uff0c\u5bf9\u4e8e\u65e9\u53d1\u73b0\u548c\u786e\u8bca\u7684\u963f\u5179\u6d77\u9ed8\u75c7\u4e2a\u6848\uff0c\u73b0\u5df2\u53ef\u4f7f\u7528\u751f\u7269\u5236\u5242\u6e05\u9664\u6c89\u79ef\u5728\u8111\u5185\u7684\u7c7b\u6dc0\u7c89\u86cb\u767d\uff0c\u6709\u52a9\u4e8e\u51cf\u6162\u75c5\u60c5\u6076\u5316\uff0c\u5ef6\u957f\u60a3\u8005\u5982\u5e38\u751f\u6d3b\u7684\u65f6\u95f4\u3002<\/p>\n\n\n\n
<\/p>\n\n\n\n
\u5434\u533b\u751f\u5f15\u7528\u8fd1\u5e74\u7684\u7814\u7a76\u6307\u51fa\uff0c\u963f\u5179\u6d77\u9ed8\u75c7\u7684\u6210\u56e0\u4e0e\u5927\u8111\u5185\u7c7b\u6dc0\u7c89\u86cb\u767d\u548ctau\u86cb\u767d\uff08TAU\uff09\u5f02\u5e38\u6c89\u79ef\u6709\u5173\uff0c\u8fd9\u4e9b\u7269\u8d28\u4f1a\u52a0\u901f\u8111\u90e8\u9000\u5316\uff0c\u5f71\u54cd\u8111\u5185\u795e\u7ecf\u7f51\u8def\u8fde\u63a5\uff0c\u5bfc\u81f4\u8ba4\u77e5\u529f\u80fd\u53d7\u635f\u3002<\/p>\n\n\n\n
\u4ee5\u5f80\u6cbb\u7597\u963f\u5179\u6d77\u9ed8\u75c7\u7684\u836f\u7269\uff0c\u4e3b\u8981\u4ee5\u6539\u5584\u60a3\u8005\u75c7\u72b6\u4e3a\u4e3b\u3002\u800c\u8fd1\u5e74\u7f8e\u56fd\u98df\u54c1\u836f\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u5df2\u6838\u51c6\u4f7f\u7528\u80fd\u591f\u6eb6\u89e3\u7c7b\u6dc0\u7c89\u86cb\u767d\u7684\u751f\u7269\u5236\u5242\u3002\u5434\u533b\u751f\u8868\u793a\uff0c\u4e34\u5e8a\u7814\u7a76\u663e\u793a\uff0c\u8fd9\u7c7b\u836f\u7269\u5c24\u5176\u9002\u7528\u4e8e\u65e9\u671f\u963f\u5179\u6d77\u9ed8\u75c7\u60a3\u8005\uff0c\u6709\u52a9\u4e8e\u5c06\u9000\u5316\u901f\u5ea6\u964d\u4f4e30%\uff0c\u51cf\u7f13\u75c5\u60c5\u6076\u5316\u3002\u4f46\u4e00\u65e6\u75c5\u60c5\u8fdb\u5165\u4e2d\u665a\u671f\uff0c\u5927\u8111\u53ef\u80fd\u5df2\u906d\u53d7\u4e0d\u53ef\u9006\u635f\u4f24\uff0c\u4f1a\u5f71\u54cd\u6cbb\u7597\u6548\u679c\u3002\u56e0\u6b64\uff0c\u53ca\u65e9\u53d1\u73b0\u53ca\u6cbb\u7597\u5bf9\u75c5\u60c5\u7ba1\u7406\u81f3\u5173\u91cd\u8981\u3002<\/p>\n\n\n\n
\u9664\u4e86\u836f\u7269\u6cbb\u7597\uff0c\u5434\u533b\u751f\u5f3a\u8c03\uff0c\u5bb6\u4eba\u6216\u7167\u987e\u8005\u7684\u652f\u6301\u4e0e\u914d\u5408\u4ea6\u76f8\u5f53\u91cd\u8981\uff0c\u4f8b\u5982\u534f\u52a9\u60a3\u8005\u8c03\u6574\u5c45\u5bb6\u73af\u5883\u53ca\u751f\u6d3b\u4e60\u60ef\uff0c\u5982\u7269\u54c1\u6446\u653e\u3001\u65e5\u5e38\u4f5c\u606f\u5b89\u6392\u7b49\uff0c\u51cf\u5c11\u60a3\u8005\u601d\u7ef4\u6df7\u4e71\u7684\u60c5\u51b5\uff1b\u533b\u5e08\u4ea6\u4f1a\u6839\u636e\u60a3\u8005\u7684\u75c7\u72b6\uff0c\u5982\u51fa\u73b0\u7126\u8651\u6216\u5fe7\u90c1\u7b49\u60c5\u7eea\u95ee\u9898\uff0c\u5f00\u7acb\u9488\u5bf9\u6027\u7684\u836f\u7269\u6216\u652f\u6301\u6cbb\u7597\uff0c\u5e2e\u52a9\u60a3\u8005\u6539\u5584\u60c5\u7eea\u72b6\u6001\u3002<\/p>\n\n\n\n
<\/p>\n\n\n\n
\u963f\u5179\u6d77\u9ed8\u75c7\u4e0e\u8111\u5185\u5f02\u5e38\u86cb\u767d\u6c89\u79ef\u6709\u76f4\u63a5\u5173\u8054\uff0c\u4e14\u5927\u8111\u5185\u7c7b\u6dc0\u7c89\u86cb\u767d\u7684\u5f02\u5e38\u6c89\u79ef\uff0c\u53ef\u80fd\u65e9\u5728\u963f\u5179\u6d77\u9ed8\u75c7\u51fa\u73b0\u75c7\u72b6\u524d15\u81f320\u5e74\u5c31\u5df2\u5b58\u5728\u3002\u4e0d\u8fc7\u5434\u533b\u751f\u5f3a\u8c03\uff0c\u5373\u4f7f\u5927\u8111\u6709\u86cb\u767d\u5f02\u5e38\u7684\u75c5\u7406\u53d8\u5316\uff0c\u4e5f\u4e0d\u4ee3\u8868\u4e00\u5b9a\u4f1a\u7f79\u60a3\u963f\u5179\u6d77\u9ed8\u75c7\uff0c\u56e0\u6b64\u9700\u8981\u7ecf\u533b\u5e08\u8bc4\u4f30\u540e\uff0c\u518d\u786e\u5b9a\u662f\u5426\u9700\u8981\u7528\u836f\u3002<\/p>\n\n\n\n
\u4e00\u65e6\u786e\u8bca\uff0c\u6ce8\u5c04\u963f\u5179\u6d77\u9ed8\u75c7\u751f\u7269\u5236\u5242\u4e5f\u6709\u4e25\u683c\u7684\u7528\u836f\u6761\u4ef6\uff0c\u5fc5\u987b\u7ecf\u4e34\u5e8a\u8bc4\u4f30\u548c\u5f71\u50cf\u5b66\u68c0\u67e5\u8bca\u65ad\u540e\uff0c\u786e\u8ba4\u5176\u8fa8\u8bc6\u8ba4\u77e5\u529f\u80fd\u969c\u788d\u662f\u7531\u7c7b\u6dc0\u7c89\u86cb\u767d\u79ef\u805a\u6240\u5f15\u8d77\uff1b\u540c\u65f6\u60a3\u8005\u4ea6\u8981\u4e86\u89e3\u7528\u836f\u98ce\u9669\uff0c\u4f8b\u5982\u53ef\u80fd\u589e\u52a0\u8111\u5185\u51fa\u8840\u7684\u98ce\u9669\uff0d\u5c24\u5176\u643a\u5e26APOE\u03b54\u57fa\u56e0\u7684\u4eba\u7fa4\uff0c\u98ce\u9669\u4f1a\u66f4\u9ad8\u3002\u7528\u836f\u524d\uff0c\u533b\u5e08\u5fc5\u987b\u4e0e\u60a3\u8005\u8be6\u7ec6\u6c9f\u901a\u6cbb\u7597\u7684\u98ce\u9669\u4e0e\u6548\u76ca\uff0c\u8fdb\u800c\u53d1\u5c55\u51fa\u5408\u9002\u7684\u6cbb\u7597\u65b9\u6848\u3002<\/p>\n\n\n\n
<\/p>\n\n\n\n
\u9999\u6e2f\u4eba\u7684\u5bff\u547d\u4f4d\u5c45\u5168\u7403\u524d\u5217\uff0c\u800c\u5e74\u7eaa\u6108\u5927\uff0c\u60a3\u4e0a\u963f\u5179\u6d77\u9ed8\u75c7\u7684\u673a\u7387\u786e\u4f1a\u6108\u9ad8\u3002\u5434\u533b\u751f\u8868\u793a\uff0c60\u5c81\u8001\u5e74\u4eba\u60a3\u75c5\u673a\u7387\u7ea6\u4e3a1%\uff0c\u4e4b\u540e\u6bcf\u589e\u52a05\u5c81\uff0c\u98ce\u9669\u4fbf\u4f1a\u7ffb\u4e00\u500d\uff0c85\u5c81\u6216\u4ee5\u4e0a\u4eba\u58eb\u60a3\u75c5\u673a\u7387\u8d85\u8fc730%\u3002<\/p>\n\n\n\n
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\u8fd1\u5e74\u6765\u4e5f\u6709\u7814\u7a76\u663e\u793a\uff0c\u4f18\u8d28\u7684\u7761\u7720\u5bf9\u5927\u8111\u5065\u5eb7\u81f3\u5173\u91cd\u8981\u3002\u7761\u7720\u671f\u95f4\uff0c\u5927\u8111\u53ef\u4ee5\u6e05\u9664\u7c7b\u6dc0\u7c89\u86cb\u767d\u53catau \u86cb\u767d\u7b49\u6709\u5bb3\u7269\u8d28\uff0c\u56e0\u6b64\u4fdd\u6301\u826f\u597d\u7684\u7761\u7720\u8d28\u91cf\uff0c\u540c\u6837\u6709\u52a9\u4e8e\u9884\u9632\u963f\u5179\u6d77\u9ed8\u75c7\u3002<\/p>\n\n\n\n
<\/p>\n\n\n\n
\u5076\u5c14\u9057\u5931\u7269\u4ef6\u6216\u5fd8\u8bb0\u4e8b\u60c5\uff0c\u4e0d\u4e00\u5b9a\u4e0e\u963f\u5179\u6d77\u9ed8\u75c7\u6709\u5173\u3002\u5434\u533b\u751f\u79f0\uff0c\u82e5\u5bb6\u4e2d\u5e74\u957f\u4eba\u58eb\u7ecf\u5e38\u9057\u5931\u94a5\u5319\u6216\u5fd8\u8bb0\u7535\u8bdd\u6446\u653e\u7684\u4f4d\u7f6e\uff0c\u751a\u81f3\u7ecf\u5e38\u5728\u719f\u6089\u7684\u73af\u5883\u8ff7\u8def\uff0c\u5bb6\u4eba\u5e94\u63d0\u9ad8\u8b66\u89c9\u3002<\/p>\n\n\n\n
\u300c\u574a\u95f4\u4e0d\u4e4f\u4e00\u4e9b\u7b80\u5355\u7684\u8ba4\u77e5\u80fd\u529b\u95ee\u5377\u53ef\u4f9b\u53c2\u8003\uff0c\u82e5\u6709\u7591\u8651\u5e94\u53ca\u65e9\u6c42\u533b\uff0c\u63a5\u53d7\u5168\u9762\u8bc4\u4f30\u3002\u533b\u5e08\u4f1a\u4ee5\u77ed\u671f\u8bb0\u5fc6\u6d4b\u8bd5\u53ca\u5176\u4ed6\u68c0\u67e5\uff0c\u786e\u5b9a\u60a3\u8005\u662f\u5426\u60a3\u6709\u963f\u5179\u6d77\u9ed8\u75c7\uff0c\u518d\u56e0\u5e94\u75c5\u60c5\u63d0\u4f9b\u9002\u5f53\u7684\u6cbb\u7597\u5efa\u8bae\u3002 \u300d<\/p>\n\n\n\n
\u5434\u70b3\u8363\u533b\u751f
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